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- Extensively drug-resistant TB (XDR-TB) occurs when resistance to second-line drugs develops.
- In some countries, loss of productivity attributable to TB approaches 7% of GDP.
- An estimated 31 percent of all TB-HIV cases in Africa are in South Africa.
- Someone in the world is newly infected with TB every second.
- An estimated 73 percent of new TB patients in South Africa are co-infected with HIV.
- The WHO calculates that the average TB patient loses three to four months of work-time and up to 30 percent of yearly household earnings.
- TB is preventable and curable.
- TB kills someone approximately every 20 seconds.
- In some TB hot-spots, up to 30% of patients are infected with drug-resistant strains.
- TB is the leading cause of death in South Africa.
- More than two billion people, one third of the world’s population, are infected with TB.
- 13 of the 15 countries with the highest estimated TB incidence rates are in Africa.
- There are thought to be 25,000 cases of XDR-TB emerging every year.
- TB is the third leading cause of death worldwide among women aged 15-44.
- South Africa ranked fifth on the list of 22 high-burden tuberculosis (TB) countries in the world.
- 94 percent of TB cases and 98 percent of TB deaths occur in developing countries.
- Among women, TB accounts for more deaths than all causes of maternal mortality.
- One-third of the more than 40 million people living with HIV/AIDS are also infected with tuberculosis.
- Curing MDR-TB can cost 1400 times more than curing drug susceptible TB.
- At any given moment, more than 13 million people around the world are suffering from an active TB infection.
- If not treated, each person with active TB can infect 10 to 15 people a year.
- TB will rob the world’s poorest countries of an estimated $1 to $3 trillion over the next 10 years.
- TB is the leading infectious killer of people with HIV/AIDS, especially in sub-Saharan Africa, where it causes up to half of all AIDS deaths.
- Multidrug-resistant TB (MDR-TB) is a form of TB that does not respond to the standard treatments using first-line drugs.
- 490,000 new MDR-TB cases are estimated to occur each year.
- 58 countries have reported at least one case of XDR-TB as of March 2010.